For off-label therapeutic use of drugs, where can pharmacists find relevant information?

The American Hospital Formulary Service (AHFS) is a comprehensive reference that provides detailed information on the therapeutic use of medications, including off-label uses. It is widely recognized for its rigor and depth of content, which includes clinical and therapeutic guidelines for various drugs. The AHFS is especially valuable for pharmacists, as it offers evidence-based evaluations and summaries of drug information that are critical when considering off-label prescribing.

Pharmacists rely on the AHFS for specific guidelines related to off-label indications, dosing regimens, and potential drug interactions. It serves as a trusted resource to ensure safe and effective treatment while navigating complex therapeutic decisions involving off-label drug use.

While other resources like the NIH database and directories of medical guidelines may also provide some information about off-label use, the AHFS is specifically curated for comprehensive drug-related information, making it the most suitable choice for pharmacists looking for details on off-label therapeutic uses. The Physicians' Desk Reference (PDR) is primarily focused on prescribing information and may not delve deeply into off-label uses as comprehensively as the AHFS.