In an ambulatory care comprehensive narcotic treatment program, by which route may patients receive methadone doses?

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In an ambulatory care comprehensive narcotic treatment program, the most common and widely accepted method for patients to receive methadone doses is orally. Methadone is formulated specifically for oral administration, which allows for effective absorption in the gastrointestinal tract and provides a controlled and steady release of the medication into the bloodstream. This route is preferred in treatment programs as it simplifies dosing procedures and enhances patient compliance.

Oral administration of methadone also avoids the complexities and potential complications associated with other routes, such as intravenous and subcutaneous, which can carry risks like infection, the need for sterile preparations, and more stringent oversight. Additionally, methadone's pharmacokinetics are optimized for oral use, enabling it to be effective in managing withdrawal symptoms and cravings in patients undergoing treatment for opioid use disorder.

The other routes mentioned are less suitable for methadone administration within the context of a treatment program, either due to practical challenges or because they are not standard methods for administering this specific medication.

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