What is one primary characteristic of Schedule II controlled substances?

Schedule II controlled substances are primarily characterized by their high potential for abuse and dependence. This classification indicates that these substances, while having accepted medical uses, can lead to severe psychological or physical dependence. Examples of Schedule II substances include opioids like morphine and stimulants such as amphetamines.

The high potential for abuse associated with these drugs requires stricter regulations governing their prescription and distribution, ensuring that they are used safely and monitored closely by healthcare professionals. Such classification reflects the balance that needs to be struck between providing therapeutic benefits and preventing misuse and addiction.

In contrast, substances available over-the-counter are not considered for this schedule, completely non-addictive substances fall into entirely different classifications, and those that can be prescribed without restrictions would not meet the criteria defined for Schedule II substances.