What is required for the proper storage of controlled substances?

For the proper storage of controlled substances, it is essential that they be stored in a locked cabinet or safe. This requirement is crucial for maintaining security and preventing unauthorized access to these potentially dangerous medications. Controlled substances have a higher potential for abuse and, therefore, are subject to strict regulatory controls. Storing them in a locked facility ensures that only authorized personnel can access them, which helps safeguard against theft, misuse, or accidental ingestion.

Regarding the other options, while room temperature storage and refrigeration may apply to certain medications or substances, they are not specific requirements for the general storage of controlled substances. Additionally, while pharmacists typically have access to controlled substances, having a locked storage area is intended to protect the substances from anyone who may not be authorized, rather than limiting access solely to pharmacists. Hence, the most critical and universally applicable requirement for the storage of controlled substances is their secure placement in a locked cabinet or safe.