Which controlled substance may be partially filled upon patient request?

Empirin with codeine #4 is classified as a Schedule III controlled substance. Under federal law, Schedule III substances can be partially filled upon patient request if certain conditions are met. This includes the patient's need for the medication due to pain management or other conditions that may require a gradual titration of the dosage without the necessity of dispensing the entire prescribed amount all at once.

Partially filling a prescription can help patients manage their medication more effectively, particularly if they are uncertain about how much they will need. This flexibility is permitted for substances that are less strictly regulated than Schedule II controlled substances, which generally have more stringent filling and refilling regulations. Choices like oxycodone, hydromorphone, and adderall are classified as Schedule II substances, which typically do not allow for partial fills except under very specific circumstances related to the dispensing and patient needs. Thus, the correct answer reflects the regulations governing prescriptions for the respective controlled substances.