Which drug requires a patient to sign an informed consent before receiving the original prescription?

The requirement for a patient to sign an informed consent prior to receiving a prescription is typically associated with medications that have significant risks or that could lead to serious side effects, requiring the patient to be fully informed of those risks. Olanzapine, an atypical antipsychotic used to treat conditions like schizophrenia and bipolar disorder, falls into this category. Patients on olanzapine may face various potential side effects, such as metabolic syndrome, sedation, and other serious neurological adverse effects.

Informed consent ensures that patients are aware of these risks and can make an informed decision about their treatment. This process is particularly critical with psychiatric medications, as they often have complex side effects and implications for a patient's overall health and well-being.

In contrast, medications like metformin, ibuprofen, and amoxicillin generally do not require a formal informed consent process, although it is always essential for healthcare providers to discuss potential risks and benefits with their patients. These other drugs are largely used for conditions that come with less severe side effects compared to olanzapine.