Which of the following are examples of Schedule I substances?

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Schedule I substances are defined as drugs that have a high potential for abuse, have no currently accepted medical use in treatment in the United States, and lack accepted safety for use under medical supervision. Lysergic acid diethylamide (LSD), listed in the choice, fits this classification perfectly. It has been recognized for its potent psychoactive effects, is illegal in most jurisdictions, and is associated with significant risks of psychological impact.

In contrast, cocaine, hydrocodone, and oxycodone are classified differently. Cocaine, although it has a high potential for abuse, can be used in medical settings for specific applications, thus placing it in a lower schedule. Hydrocodone and oxycodone are recognized for their medical uses, particularly in pain management, and are classified as Schedule II substances, which, while still controlled, have accepted medical applications.

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