Which of the following drug products must be purchased by pharmacies using DEA Form 222?

Pharmacies are required to use DEA Form 222 to purchase controlled substances that fall under certain schedules as defined by the Drug Enforcement Administration (DEA). MS Contin, which contains morphine, is classified as a Schedule II controlled substance. Schedule II drugs are subject to stringent regulations, including the requirement for pharmacies to order them using DEA Form 222. This form serves as a means for the DEA to track the procurement of these high-risk medications, helping to prevent misuse and diversion.

In contrast, Vicodin (which contains hydrocodone) is a Schedule III controlled substance and does not require a DEA Form 222 for purchase. Amoxicillin is an antibiotic and is not a controlled substance at all. Similarly, Concerta, while being a Schedule II stimulant, is often categorized differently in practice, though it is also subject to the DEA regulations similar to MS Contin. However, the critical factor here is that MS Contin is a prime example of a drug that necessitates the use of the DEA Form 222 for its purchase due to its specific Schedule II classification, aligning with the regulations put in place for such potent medications.